Creating Subject-Specific Mathematical Models to Understand the Brain

Grant number: DP200102600 | Funding period: 2020 - 2023

Completed

Abstract

This project aims to develop a mathematical framework that bridges the different scales of brain activities to provide a new tool for understanding the brain. Methods will be developed that unify individual neural activity with large scale brain activity. The approach will be validated by comparing predictions of interconnected models of neural populations (called mean-field models) to experimental data. The creation of subject-specific models from data is important, as there is large variability in neural circuits between individuals despite seemingly similar network activity. The intended outcome is new insights into the processes that govern brain function and methods for improving functi..

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University of Melbourne Researchers

David Grayden

Pip Karoly

Mark Cook